Abstract: Burning mouth syndrome (BMS), also known as orofacial pain syndrome or oral burning syndrome, is a chronic disease characterized by burning pain in the oral mucosa, which severely affects patients’ quality of life. In recent years, laser therapy has gradually become a research hotspot for BMS treatment due to its advantages such as non-invasiveness, analgesia, and promotion of tissue repair. This article systematically reviews the current research status of laser treatment for BMS at home and abroad in recent years. By analyzing the action mechanisms and clinical applications of low-intensity laser therapy, it is pointed out that lasers can significantly improve BMS symptoms with fewer adverse reactions, providing evidence-based medical support for clinicians in applying laser therapy for BMS.
Key words: burning mouth syndrome; photobiomodulation; low-intensity laser therapy; pain management; treatment program
（Acta Laser Biology Sinica, 2025, 34(6): 489-495）