Abstract: With the widespread application of ultraviolet laser technology, the potential risk of damage to biological tissues, especially the eyes, has been closely monitored. The issue of eye damage caused by ultraviolet lasers has always been a hot topic among researchers studying the effects of eye damage. The spectral range of ultraviolet lasers covers a wavelength range of 200 nm to 400 nm, and the complex structure of the eye is responsible for that it responds differently to ultraviolet light of different wavelengths. This paper aims to review the damage effects of ultraviolet lasers on the eyes, organize relevant literature, and discuss the mechanisms of damage, clinical applications, current protective measures, and future research directions. Determination of the biological damage effects of ultraviolet lasers on the eyes and the mechanisms underlying ultraviolet laser eye damage is beneficial for improving related medical and repairment technologies and is of great significance for the formulation of effective safety protection standards.
Key words: ultraviolet laser; eye damage; photokeratitis; photochemical damage; protection and repair technology
（Acta Laser Biology Sinica, 2025, 34(5): 401-408）