Exploration of the Application Prospects of Photobiomodulation Therapy in the Treatment of Ulcerative Colitis

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Acta Laser Biology Sinica ›› 2025, Vol. 34 ›› Issue (4) : 296-303.

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Abstract: As a non-invasive, low-cost and low-risk treatment technology, photobiomodulation therapy (PBMT) shows a unique application prospect in the treatment of ulcerative colitis (UC). This article introduces the pathogenesis of UC and the current application status of PBMT in clinical practice. It is analyzed that this therapy is expected to play a synergistic role with existing treatment methods such as 5-aminosalicylic acid (5-ASA) preparations and biological agents. At the same time, this article also analyzes deeply the possible challenges and safety risks in the clinical application of PBMT. It is recommended that future research should focus on formulating operation methods, adjusting treatment parameters, developing individualized treatment plans, and adding safety measures, so as to promote the clinical transformation of PBMT in the treatment of UC.
Key words: biological optics; photobiomodulation therapy; low energy light source; ulcerative colitis; treatment
（Acta Laser Biology Sinica, 2025, 34(4): 296-303）

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WU Yangguang, QU Haitao, ZHANG Shuangxi, YUAN Hao. Exploration of the Application Prospects of Photobiomodulation Therapy in the Treatment of Ulcerative Colitis[J]. Acta Laser Biology Sinica. 2025, 34(4): 296-303