The human coronavirus disease COVID-19, caused by the new coronavirus SARS-CoV-2 in Wuhan, China, spread rapidly in China and more than 70 countries globally in just  over 2 months. Due to its high morbidity and mortality rate, human beings are under great threat. Some scientists have promptly conducted indepth researches on the source and evolution of SARS-CoV-2, morphological characteristics and gene structure, molecular mechanisms of infection and pathogenicity. Significant progress has been made, providing an important basis for scientific prevention and control of COVID-19. According to the current research progress, the article puts forward the ideas for the development of COVID19 virus vaccines, antibodies and inhibitors, which has certain reference value for the study of the core technology in COVID19 prevention and control.