NAC transcription factors play an important role in plant growth development and resistance to stress. In our previous studies, the Slnac2gene was cloned from Suaeda liaotungensis and transformed into Arabidopsis. SlNAC2 enhanced the salt tolerance of transgenic Arabidopsis. In this study, we screened the differentially expressed genes in transgenic Slnac2 Arabidopsis compared to the wild type by cDNA microarray. There are 1 258 genes which expressed more than twofold in transgenic Arabidopsis. The results of GO enrichment analysis showed that the molecular functionrelated genes accounted for 34.06%, the cellrelated genes accounted for 33.13%, and the biological processrelated genes accounted for 32.81%. KEGG（Kyoto Encyclopedia of Genes and Genomes pathways enrichment）analysis showed that 1 258 genes were involved in 63 different signaling pathways including plant hormone signal transduction, ribosome plantpathogen interaction, ascorbate and aldarate metabolism, etc. Some differential genes were verified by realtime PCR, and the results were consistent with those of the gene chip. In summary, SlNAC2 can regulate the expression of numerous downstream genes and improve plant viability under stress.