The relationship between the gene polymorphism of 〖WTBX〗interleukin 17A〖WTBZ〗  and prognosis of gastric cancer was investigated129 cases were included in the survival analysis, which were divided into the death group and the survival groupThe genotypes of rs3748067 and rs17880588 were detected using gene sequencing methodThere were 3 genotypes of T/T, C/T, C/C for rs17880588And there were 2 genotypes of A/G and G/G for rs3748067The frequencies of genotype and allele were compared
between the survival group and the death groupIt is found that the rs3748067 frequency of genotype C/T is higher in the death group, and the difference was statistically significant (P<005)The distribution frequency of heterozygous C/T genotype in the survival group was lower than that in the death group (OR=2051, CI=0016~1420), which might be a risk factor for the prognosis of gastric cancerThere was no significant difference of the frequency of the two genotypes A/G and G/G in loci rs1788058 (P>005)The SNP rs3748067 of IL17A gene might be correlated with the prognosis of gastric cancer
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