摘　要：随着医疗光电产品的升级，人们对便携式医疗设备和全天候监测医学传感器的需求日益增大。得益于有机电致发光二极管（OLED）的柔性、可拉伸、轻薄、均匀辐照和贴合皮肤表面等优点，其正成为可穿戴式生物医学设备的新型光源。本文详细介绍了OLED在光动力疗法、光电容积脉搏监测、光吸收式血氧监测、光遗传学和光生物调制等领域的应用进展，充分展示了OLED在医疗光电产品中的应用潜力。为了满足临床应用对光源的需求，提高OLED发光功率及延长其寿命是未来的重要发展方向。
关键词：有机电致发光二极管；光动力疗法；脉搏血氧仪；光遗传学；光生物调制
中图分类号：R318.51　　　　　　文献标志码：ADOI：10.3969/j.issn.1007-7146.2021.03.001

Abstract: The demand for portable medical equipment and all-day health monitor continues to increase with the development of the medical industry. Benefiting from the advantages such as flexibility, stretchability, light weight, uniform irradiation and jointing skin surface, organic light-emitting diodes (OLED) are becoming a new type of light source for wearable biomedical devices. In this review, recent advances of OLED in photodynamic therapy, photoplethysmography, oximeter, optogenetics, and photobiomodulation are summarized, and the potential application of OLED in wearable healthcare is highlighted. The future trends of OLED will be focused on the development of long-lived devices with high power density as the light sources for clinical applications.
Key words: organic light-emitting diode; photodynamic therapy; pulse oximeter; optogenetics; photobiomodulation
（Acta Laser Biology Sinica, 2021, 30(3): 193-199）