Abstract:Abstract: Baicalin, a kind of flavonoid substance derived from the root part of Scutellaria baicalensis Georgi, which is the main active ingredient of the plant. The pharmacological effect of baicalin is extensive and it shows great potential in its anti-inflammatory effect, and its main mechanisms include regulating intestinal flora, inhibiting NF-κB nuclear transposing, increasing the expression of related microRNA, inhibiting autophagy, and regulating Treg/Th17 balance. This article reviewed the research progress of baicalin on the anti-inflammatory mechanism at home and abroad, which provides a basis for its clinical application and further study.
Key words: baicalin; inflammation; intestinal flora; NF-κB; miRNA
(Acta Laser Biology Sinica, 2021, 30(5): 400-405)
引用本文:
周 颖,张 珂,庄 煜,胡国良. 黄芩苷抗炎作用机制的研究进展[J]. 激光生物学报, 2021, 30(5): 400-405.
ZHOU Ying, ZHANG Ke, ZHUANG Yu, HU Guoliang. Progress in Anti-inflammatory Mechanism of Baicalin. journal1, 2021, 30(5): 400-405.