（南京理工大学电子工程与光电技术学院，南京 210094）

摘　要：本文基于圆柱-双折射的皮肤真皮层简化模型，研究了人体皮肤偏振特性随其结构参数的变化特性。该工作第一次利用偏振敏感光学相干层析成像系统所测得的人体皮肤的双折射参数值，分析了其双折射、二相色性以及退偏特性随结构参数的变化而变化的特性。该研究结果对于解释偏振试验测量结果、进行临床人体皮肤病的诊断以及治疗效果的在体监测具有重要的帮助。

关键词：人体皮肤模型；双折射特性；二相色性；成像系统；退偏特性

中图分类号：TN247                             文献标志码：ADOI：10.3969/j.issn.1007-7146.2024.02.005

(School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing 210094, China)

Abstract: In this paper, based on a simplified dermis model of cylinder-birefringence, the variation of polarization properties of human skin with its structural parameters was studied. To the best of our knowledge, for the first time, the birefringence parameters of human skin measured by polarization-sensitive optical coherence tomography system was used to analyze the changes of birefringence, dichroism and depolarization with the change of structural parameters. The results of this study are important for interpreting the results of polarization experiments, diagnosing human skin diseases and monitoring the effects of treatment in vivo.

Key words: human skin model; birefringence; dichroism; imaging system; depolarization

（Acta Laser Biology Sinica, 2024, 33(2): 133-142）