摘　要：光生物调节疗法作为口腔黏膜病治疗的辅助手段发展迅速，它通过细胞吸收光子能量，产生光化学效应，从而调节各种各样的生物过程来达到治疗目的。本文就减少炎症、加速组织愈合、缓解疼痛以及光生物调节的双向剂量作用4个方面进行综述，并深入探讨了其作用机制，以便为临床医师应用光生物调节疗法治疗口腔黏膜病提供更好的临床决策和依据。
关键词：光生物调节；治疗；口腔黏膜病；发色团；双相剂量反应
中图分类号：R781.5                         文献标志码：A               DOI：10.3969/j.issn.1007-7146.2023.05.003

Abstract: Photobiomodulation (PBM) as an adjunct method for the treatment of oral mucosal diseases has developed rapidly. It is through the absorption of photon energy by cells, produce photochemical effects, and thus regulate a variety of biological processes to achieve therapeutic purposes. In this paper, the four aspects of reducing inflammation, accelerating tissue healing, relieving pain and bidirectional dose of PBM are reviewed, and the mechanism of their action is deeply discussed in order to provide clinicians with better clinical decision and basis for the treatment of oral mucosal diseases with PBM therapy.
Key words: photobiomodulation; treatment; oral mucosal disease; chromophore; biphasic dose response
（Acta Laser Biology Sinica, 2023, 32(5): 403-413）