摘　要：玫瑰痤疮是一种主要累及面中部的慢性炎症性损容性皮肤病，确切的病因及发病机制尚未完全阐明，临床治疗棘手。尽管以往的局部外用药物和系统口服药物治疗对红斑毛细血管扩张型玫瑰痤疮（ETR）有一定的效果，但用药周期长、起效慢且容易反弹复发，特别是对潮红、灼热等主观症状改善不明显，患者的依从性差，满意度低，易存在焦虑抑郁等心理问题。近年来，随着脉冲染料激光、强脉冲光、Nd:YAG激光、KTP激光、Pro-Yellow激光、光生物调节疗法等多种光电技术广泛应用于临床，ETR的治疗方案选择性更广了，整体治疗效果得到了提升，医患双方的满意度也较前有所提高。本文对目前多种光电技术在ETR治疗中的应用进展作一综述。
关键词：玫瑰痤疮；红斑；血管扩张；激光；光生物调节
中图分类号：R758.73+4                           文献标志码：A                DOI：10.3969/j.issn.1007-7146.2022.04.003

Abstract: Rosacea is a chronic inflammatory skin disease mainly involving the middle face. The exact etiology and pathogenesis have not been fully elucidated, and the clinical treatment is difficult. Although the previous topical drugs and systematic oral drugs have some effects on erythematotelangiectatic rosacea (ETR), they have a long medication cycle, slow onset, and are easy to rebound and relapse. In particular, the subjective symptoms such as flushing and burning are not significantly improved. The compliance and satisfaction of patients are poor and low, and patients are prone to anxiety, depression and other psychological problems. In recent years, with the widespread application of pulsed dye laser, intense pulsed light, Nd:YAG laser, KTP laser, Pro-Yellow laser, photobiomodulation therapy and other photoelectric technologies in clinical treatment of ETR, the options showed a wider range, the overall therapeutic effects are promoted, the satisfactions of both doctors and patients are improved. This article reviews the application of various photoelectric techniques in the treatment of ETR.
Key words: rosacea; erythema; vasodilation; laser; photobiomodulation
（Acta Laser Biology Sinica, 2022, 31(4): 303-310）