摘　要：茶中多酚类化合物主要成分儿茶素及其衍生物被发现具有较强的抗病毒作用，对多种病毒特别是流感病毒有较强的抑制作用，被认为是一种潜在的抗病毒药物前体。研究发现儿茶素及其衍生物可能成为抗流感病毒药物设计研究中优先考虑的化合物。本文对近二十年来国内外儿茶素及其衍生物等的抗流感病毒作用、作用机制、临床研究以及应用开发等方面进行了综述与分析，为茶中多酚类化合物抗流感病毒的进一步研究提供参考。
关键词：茶；茶多酚；儿茶素；茶黄素；流感病毒

Absract: Catechins and their derivatives, the main component of polyphenols in tea, have been found to have strong antiviral effects. They have strong inhibitory effects on various viruses, especially for influenza virus, which is considered as a potential antiviral precursor. It was found that tea catechins and their derivatives may be the priority compounds in the design of anti-influenza drugs. This paper reviews the history of the inhibition of influenza virus by catechins and their derivatives, and reviews its action mechanism and clinical research progress, which provides reference for the further research of tea polyphenols against influenza virus.
Key words: tea; tea polyphenols; catechin; theaflavin; influenza virus