为探讨莫匹罗星联合氦氖激光照射治疗新生儿脐炎的临床疗效，本研究选取了2013至2018年新生儿脐炎患儿86例，通过对照研究，按治疗方法不同分为观察组（莫匹罗星+氦氖激光照射）与对照组（莫匹罗星）各43例，观察两组患儿新生儿脐炎愈合时间及不良反应发生情况。试验发现观察组平均愈合时间为（4.186±0.194）d，总有效率为100%；对照组平均愈合时间为（5.189±0.238）d，总有效率为86%；观察组愈合时间显著高于对照组（P<0.05）。两组患儿在治疗期间均未发现皮肤红疹等不良事件。研究结果显示，莫匹罗星联合氦氖激光照射治疗新生儿脐炎的临床疗效确切，安全性高。

To investigate clinical effectiveness of mupirocin and HeNe laser radiation on neonatal omphalitis through the controlled study. 86 cases of neonatal omphalitis was selected from 2013 to 2018, divided into observation group （mupirocin + HeNe laser therapy)and the control group （mupirocin)according to different treatments, with 43 cases in each group. Neonatal omphalitis healing time and adverse event was recorded .It was found that the average healing time of observation group was （4.186±0.194)d, the total effective rate was 100%, and average healing time was （5.189±0.238)d, the total effective rate was 86%on the control group. Healing time of observation group were significantly higher than that of control group （P<0.05). Adverse events such as skin rash were not found in two groups. Study shows that mupirocin  combined with HeNe laser radiation therapy for the treatment of neonatal omphalitis have good  clinical curative effect, high safety.