超连续谱（SC）光源是一种宽光谱、高亮度、眼睛危害大的新光源，有关它致视网膜损伤研究却未见报道。为了观察SC光源致视网膜损伤特点和修复过程，试验将波长420~750 nm的SC光源与532 nm激光进行比较，采用两者平行光入射,在0.1 s照射时间，3 mm角膜光斑直径条件下，用略高于视网膜损伤阈值的功率照射青紫蓝灰兔视网膜；通过检眼镜和HE染色观察视网膜照后4 h，1、3、7、14 d损伤修复过程。SC光源和532 nm激光致视网膜的损伤在检眼镜下为灰色小圆斑。照后4 h出现视网膜外核层固缩深染，感光细胞外节与视网膜色素上皮层（RPE）粘连；随后RPE层色素增生、损伤的外核层细胞丢失，损伤进行性加重；3 d后色素细胞开始向外核层和内核层迁移，胶质细胞填充损伤区域。由此可见，波长420~750 nm的SC光源主要损伤视网膜外核层和RPE层，后期色素颗粒和胶质细胞填充损伤区域。其视网膜损伤特点和修复过程与532 nm激光类似。

Supercontinuum （SC)source is a new source with wide spectrum, high brightness and great harm to the eyes. However, there is no report on the retinal damage and the following healing  process. In order to observe the retinal damage induced by SC source and compare with that induced by 532 nm laser. The chinchilla grey rabbit retinas were exposed to paralleled 420~750 nm SC source and 532 nm laser at the power level slightly higher than damage threshold. The incident beam diameter was  3 mm. The exposure duration was 0.1 s. The retinal damage and the repair process were observed by ophthalmoscope and HE staining at  4 h, 1, 3, 7 and 14 d after exposure. The retinal damage caused by SC source and 532 nm laser appeared as small grey spots under ophthalmoscope. 4 hours after irradiation, the outer nuclear layer （ONL)became a condensation state and deepstained, the outer segments adhered to the retinal pigment epithelium （RPE)layer. Then RPE pigmentation and the loss of damaged ONL cells aggravated progressively. 3 days later, the pigmented cells began to migrate to ONL and INL layers, and the glial cells filled in the damaged area. Thus it can be seen that 420~750 nm SC source mainly damages the ONL and RPE layer of retina, and at a later stage lately the damaged area is filled with pigment granules and the glial cells, which are similar to those of 532 nm laser.