用超声驱动方法合成了CdSe/TiO₂复合纳米粒子，并通过扫描电镜(SEM)、透射电镜(TEM)、X射线衍射(XRD)、紫外可见光(UVVis)吸收光谱和荧光(FS)光谱对CdSe/TiO₂复合纳米粒子进行表征。使用CCK-8法测定CdSe/TiO₂对白血病细胞的可见光光催化活性并通过SEM研究HL60细胞的表面超微结构形态。实验结果表明，用CdSe/TiO₂复合纳米粒子处理的组中观察到明显的HL60细胞生长抑制，并且HL60细胞在CdSe掺杂TiO₂复合纳米粒子作用下的PDT效率显著高于TiO₂，表明可以通过CdSe的修饰有效增强TiO₂的可见光光催化活性。此外，CdSe/TiO^₂在可见光辐照下在4 μg/mL的终值浓度下显示非常高的光动力效率，达76%。荧光光谱分析表明，CdSe/TiO₂复合纳米粒子可能通过分离光生空穴电子对提高此复合纳米粒子的光催化活性，从而提高CdSe/TiO₂对HL60细胞的PDT灭活效率。

CdSe/TiO₂composite nanoparticles were synthesized by ultrasounddriven approach and characterized by SEM，TEM，XRD，UVVis and FS．The visible light photocatalytic activities of CdSe/TiO₂ on leukemia HL60 cells were investigated by CCK-8 approach and the ultrastructural morphology of HL60 cells was also studied by SEM．The  experimental results indicated that an obvious inhibition of leukemia HL60 cells growth would be observed in groups treated with CdSe/TiO2 composite nanoparticles，and the PDT effiency in  the presence of CdSe doped TiO₂ was significantly higher than that of TiO₂，revealing that the visible light photocatalytic activities of TiO₂ could be efficiency enhanced by the modification of CdSe．Additionally，CdSe/TiO₂ can exhibit a very high photodynamic efficiency of 76% at a final indicated concentration of 4 μg/mL under visible light irradiation．The fluorescence spectrum analysis shows that the CdSe/TiO₂ composite nanoparticles could improve the photocatalytic activity of the composite nanoparticles by separating the photogenerated hole pairs，thus enhancing the PDT inactivation efficiency of HL60 cells．