Abstract：A total of 146 skin lesions were reported in 81 patients were used to evaluate the therapeutic effect of two high energy ultrapulsed CO2 laser modes on seborrheic keratosis(SK), which were randomly divided into A and B groups, with 73 sites in each group. Group A was treated with ultrapulsed mode, group B was treated with lattice laser mode. The efficacy, the degree of pain during treatment, the average number of treatments, the time of scab off, the duration of residual erythema retreat, and the adverse reactions were observed and compared between the two groups. After the treatment, the total cure rates of A and B were 100% and 95.89%, respectively, with no significant difference(P＞0.05). Comparison of the time of scab off, the duration of residual erythema retreat, and average number of treatments were statistically significant(P＜0.05). According to the rank sum test, the total adverse reactions of the two groups were statistically significant(Z=-3.129, P=0.002), but there was no significant difference in the further single adverse reaction(P＞0.05). It is found that the lattice mode and ultrapulsed mode of high energy ultrapulsed CO2 laser are effective in treating SK, but it is safer than ultrapulsed mode with less trauma, faster healing, less adverse reactions.
引用本文:
王怀湘，李建明. 两种高能量超脉冲CO2点阵激光模式治疗脂溢性角化病的疗效比较与分析[J]. 激光生物学报, 2018, 27(4): 345-348.
WANG Huaixiang, LI Jianming. Comparison and Analysis of the Therapeutic Effects of Two High EnergyUltrapulsed CO2 Fractional Laser Modes in the Treatment. journal1, 2018, 27(4): 345-348.
