Abstract：The optical absorption of exogenous contrast agents in conventional photoacoustic imaging is mainly concentrated in the visible region and the traditional near infrared region (NIR, 750~900 nm). The development of nearinfrared-II (NIR-II, 1 000~1 700 nm) nanoprobes with higher optical tissue penetration depth is of great significance for photoacoustic imaging of deep tissue in vivo. In this paper, semiconductor singlewalled carbon nanotubes with optical absorption peaks of about 1 000 nm were selected as the exogenous contrast agent for nearinfraredⅡphotoacoustic imaging. The strong photoacoustic effect was tested under nearinfraredⅡlaser excitation. Furthermore, the deep photoacoustic imaging of the phantom tissue was obtained by embedding the nanomaterial in different depths of the tissuemimic phantom. The imaging depth can reach 1.5 cm. Experimental results show that semiconductor singlewalled carbon nanotubes (SWCNTs) with nearinfraredⅡ optical absorption have great potential in photoacoustic imaging of deep tissues in vivo.
引用本文:
崔丹丹，石玉娇. 半导体型单壁碳纳米管用于近红外二区(NIR-Ⅱ)深层组织光声成像[J]. 激光生物学报, 2019, 28(5): 463-467.
CUI Dandan, SHI Yujiao. Semiconductor Singlewalled Carbon Nanotubes for Deep Tissues NearInfraredII Photoacoustic Imaging. journal1, 2019, 28(5): 463-467.
