Abstract:Abstract: Long non-coding RNA (lncRNA) are a group of non-coding RNA that consist of more than 200 nucleotides. A review of the literature indicates that a large amount of lncRNA expression changes abnormally during the development of lung cancer. These lncRNA mainly affect the pathophysiological process of lung cancer by regulating the proliferation, apoptosis, migration, and autophagy of lung cancer cells. Recently, research on anti-lung cancer of traditional Chinese medicine targeting lncRNA is increasing. This article mainly reviews the abnormal expression of lncRNA and its mechanism of lncRNA action and summarizes the research progress of lung cancer treatment through traditional Chinese medicine with lncRNA as therapeutic target, be expecting to provide new methods and new ideas for the treatment and research of lung cancer.
Key words: lncRNA; lung cancer; Chinese medicine; diagnosis; therapy
引用本文:
李小娜,李开瑞,宋 岚. lncRNA调控肺癌及以lncRNA为靶点的中药抗肺癌治疗的研究进展[J]. 激光生物学报, 2020, 29(6): 489-495.
LI Xiaona, LI Kairui, SONG Lan. Research Progress in the Regulation of Lung Cancer by lncRNA and the Anti-lung Cancer Treatment by Chinese Medicine Targeting lncRNA#br#. journal1, 2020, 29(6): 489-495.