(School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing 210094, China)

Abstract: In this paper, based on a simplified dermis model of cylinder-birefringence, the variation of polarization properties of human skin with its structural parameters was studied. To the best of our knowledge, for the first time, the birefringence parameters of human skin measured by polarization-sensitive optical coherence tomography system was used to analyze the changes of birefringence, dichroism and depolarization with the change of structural parameters. The results of this study are important for interpreting the results of polarization experiments, diagnosing human skin diseases and monitoring the effects of treatment in vivo.

Key words: human skin model; birefringence; dichroism; imaging system; depolarization

（Acta Laser Biology Sinica, 2024, 33(2): 133-142）