Abstract：Abstract: Ferroptosis is a new type of iron-dependent programmed cell death, which is different from apoptosis, necrosis and pyrodeath. Its main characteristics are iron accumulation and lipid peroxidation. Studies have shown that ferroptosis plays an important role in kidney related diseases such as acute kidney injury and renal cancer, whereas its exact mechanism has not been fully revealed. With the development of the research on the mechanism of iron death, ferroptosis shows a good application prospect in the treatment of renal diseases. In this paper, the mechanism of ferroptosis and the research progress in renal related diseases are reviewed, in order to provide new ideas and research directions for the treatment of renal related diseases.
Key words: renal; ferroptosis; disease; lipid peroxidation; renal cancer
（Acta Laser Biology Sinica, 2021, 30(4): 289-295）
引用本文:
孙佳宾，岳明豪，刘 赞，夏舜尧，修有成. 铁死亡相关机制及其在肾脏相关疾病中的研究进展[J]. 激光生物学报, 2021, 30(4): 289-295.
SUN Jiabin, YUE Minghao, LIU Zan, XIA Shunyao, XIU Youcheng. Research Progress in the Mechanism of Ferroptosis and Its Role in Renal Related Diseases. journal1, 2021, 30(4): 289-295.
